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UniProtKB/Swiss-Prot entry Q9ZKB2

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G6PD_HELPJ
Primary accession number Q9ZKB2
Secondary accession numbers None
Integrated into Swiss-Prot on December 1, 2000
Sequence was last modified on May 1, 1999 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 55)
Name and origin of the protein
Protein name Glucose-6-phosphate 1-dehydrogenase
Synonyms G6PD
EC 1.1.1.49
Gene name
Name: zwf
OrderedLocusNames: jhp_1027
From
Helicobacter pylori J99 (Campylobacter pylori J99) [TaxID: 85963] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; Helicobacteraceae; Helicobacter.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/16495; PubMed=9923682 [NCBI, ExPASy, EBI, Israel, Japan]
Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C., Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G., Tummino P.J., Caruso A., Uria-Nickelsen M., Mills D.M., Ives C., Gibson R., Merberg D., Mills S.D., Jiang Q., Taylor D.E., Vovis G.F., Trust T.J.;
"Genomic sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori.";
Nature 397:176-180(1999).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE001439; AAD06598.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR F71859; F71859.
RefSeq NP_223744.1; -.
3D structure databases
HSSP P11411; 1DPG. [HSSP ENTRY / PDB]
ModBase Q9ZKB2.
Enzyme and pathway databases
BioCyc HPYL85963:JHP1027-MON; -.
Ontologies
GO
GO:0005488; Molecular function: binding (inferred from electronic annotation from InterPro).
GO:0004345; Molecular function: glucose-6-phosphate dehydrogenase activity (inferred from electronic annotation from InterPro).
GO:0006006; Biological process: glucose metabolic process (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001282; Glc-6-P_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR23429; G6PDH; 1.
Pfam PF02781; G6PD_C; 1.
PF00479; G6PD_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000110; G6PD; 1.
PRINTS PR00079; G6PDHDRGNASE.
ProDom PD001129; G6PD; 1.
[Domain structure / List of seq. sharing at least 1 domain]
PROSITE PS00069; G6P_DEHYDROGENASE; 1.
ProtoNet Q9ZKB2.
Genome annotation databases
GeneID 889664; -.
GenomeReviews AE001439_GR; jhp_1027.
KEGG hpj:jhp1027; -.
NMPDR fig|85963.1.peg.1022; -.
Phylogenomic databases
HOGENOM Q9ZKB2; -.
Genome annotation databases
CMR Q9ZKB2; jhp_1027.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Carbohydrate metabolism; Complete proteome; Glucose metabolism; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   425  425     Glucose-6-phosphate 1-dehydrogenase. PRO_0000068124
ACT_SITE   225   225        Proton acceptor (By similarity). 
BINDING   12    12        NADP (By similarity). 
BINDING   44    44        NADP (By similarity). 
BINDING   165   165        Substrate (By similarity). 
BINDING   169   169        Substrate (By similarity). 
Sequence information
Length: 425 AA [This is the length of the unprocessed precursor] Molecular weight: 49456 Da [This is the MW of the unprocessed precursor] CRC64: 3A7FDD9200DB0D50 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MLDFDLVLFG ATGDLAMRKL FVSLYEIYIH YGFKNDSRII ASGRKELSNE EFLALLCEKT 

        70         80         90        100        110        120 
QLHSREKGEE FLTHISYLRV RLDNPKDFEE LSKIATNNKP LIFYFSISPS FFATTAQNLA 

       130        140        150        160        170        180 
QNALNHANTR LILEKPLGHD LKTCKEIFQS ISAFFKEEQI FRIDHYLGKK GVQNILELRL 

       190        200        210        220        230        240 
NNPILNILWD QISAVEICVY ETLGVEERGE FYDKIGALRD MVQNHLLQVL SLIATDLPND 

       250        260        270        280        290        300 
LKDLRQEKIK VLKTLQPPKD FTKQVIRAQY QGYRDENKVH KESQTETFVA IKAFLDTPKF 

       310        320        330        340        350        360 
KGVPFYLKHA KKMPRNQASV KIHFNAVNTL EFFLSQDKIT LTLKDHQNPL ILETHNKQEF 

       370        380        390        400        410        420 
LQPYAKLLYD AIPNNHYNFA HQLELEASWV FIDTLIEGFI NNATPLYSYE SHNLNESEFL 


KPLYQ
Q9ZKB2 in FASTA format

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