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UniProtKB/Swiss-Prot entry Q9Z6L0


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AK_CHLPN
Primary accession number Q9Z6L0
Secondary accession numbers Q9JQD3 Q9K1X9
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on May 1, 1999 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 54)
Name and origin of the protein
Protein name Aspartokinase
Synonyms EC 2.7.2.4
Aspartate kinase
Gene name
Name: lysC
OrderedLocusNames: CPn_1049, CP_0803, CpB1090
From
Chlamydia pneumoniae (Chlamydophila pneumoniae) [TaxID: 83558] [HAMAP proteome]
Taxonomy Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae; Chlamydophila.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CWL029;
DOI=10.1038/7716; PubMed=10192388 [NCBI, ExPASy, EBI, Israel, Japan]
Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W., Olinger L., Grimwood J., Davis R.W., Stephens R.S.;
"Comparative genomes of Chlamydia pneumoniae and C. trachomatis.";
Nat. Genet. 21:385-389(1999).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AR39;
DOI=10.1093/nar/28.6.1397; PubMed=10684935 [NCBI, ExPASy, EBI, Israel, Japan]
Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J., Gwinn M.L., Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M.;
"Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39.";
Nucleic Acids Res. 28:1397-1406(2000).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=J138;
DOI=10.1093/nar/28.12.2311; PubMed=10871362 [NCBI, ExPASy, EBI, Israel, Japan]
Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.;
"Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA.";
Nucleic Acids Res. 28:2311-2314(2000).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=TW-183;
Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K.;
"The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis.";
Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE001363; AAD19186.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE002161; AAF38602.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BA000008; BAA99256.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE017160; AAP99019.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR F86621; F86621.
G81537; G81537.
H72002; H72002.
RefSeq NP_225243.1; -.
NP_301104.1; -.
NP_445342.1; -.
NP_877362.1; -.
3D structure databases
ModBase Q9Z6L0.
Enzyme and pathway databases
BioCyc CPNE115711:CP_0803-MON; -.
CPNE115713:CPN1049-MON; -.
CPNE138677:CPJ1049-MON; -.
CPNE182082:CPB1090-MON; -.
Ontologies
GO
GO:0004072; Molecular function: aspartate kinase activity (inferred from electronic annotation from InterPro).
GO:0019877; Biological process: diaminopimelate biosynthetic process (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001048; Asp/Glu/Uridylate_kinase.
IPR001341; Asp_kin_reg.
Graphical view of domain structure.
Gene3D G3DSA:3.40.1160.10; Aa_kinase; 1.
Pfam PF00696; AA_kinase; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00657; asp_kinases; 1.
PROSITE PS00324; ASPARTOKINASE; 1.
ProtoNet Q9Z6L0.
Genome annotation databases
GeneID 1467769; -.
895115; -.
919815; -.
962716; -.
GenomeReviews AE002161_GR; CP_0803.
AE009440_GR; CpB1090.
AE001363_GR; CPn_1049.
BA000008_GR; lysC.
KEGG cpa:CP0803; -.
cpn:CPn1049; -.
cpt:CpB1090; -.
TIGR CP_0803; -.
Phylogenomic databases
HOGENOM Q9Z6L0; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Diaminopimelate biosynthesis; Kinase; Lysine biosynthesis; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   440  440     Aspartokinase. PRO_0000066674
CONFLICT   145   145        R -> S (in Ref. 2; AAF38602). 
Sequence information
Length: 440 AA [This is the length of the unprocessed precursor] Molecular weight: 48382 Da [This is the MW of the unprocessed precursor] CRC64: 28E11BE300BAB959 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSKIVYKFGG TSLATAENIC LVCDIICKDK PSFVVVSAIA GVTDLLVDFC SSSLREREEV 

        70         80         90        100        110        120 
LRKIEGKHEE IVKNLAIPFP VSTWTSRLLP YLQHLEISDL DFARILSLGE DISASLVRAV 

       130        140        150        160        170        180 
CSTRGWDLGF LEARSVILTD DSYRRASPNL DLMKAHWHQL ELNQPSYIIQ GFIGSNGLGE 

       190        200        210        220        230        240 
TVLLGRGGSD YSATLIAELA RATEVRIYTD VNGIYTMDPK VISDAQRIPE LSFEEMQNLA 

       250        260        270        280        290        300 
SFGAKVLYPP MLFPCMRAGI PIFVTSTFDP EKGGTWVYAV DKSVSYEPRI KALSLSQYQS 

       310        320        330        340        350        360 
FCSVDYTVLG CGGLEEILGI LESHGIDPEL MIAQNNVVGF VMDDDIISQE AQEHLVDVLS 

       370        380        390        400        410        420 
LSSVTRLHHS VALITMIGDN LSSPKVVSTI TEKLRGFQGP VFCFCQSSMA LSFVVASELA 

       430        440 
EGIIEELHND YVKQKAIVAT 

Q9Z6L0 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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