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UniProtKB/Swiss-Prot entry Q9YAW4

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GYAR_AERPE
Primary accession number Q9YAW4
Secondary accession numbers None
Integrated into Swiss-Prot on May 10, 2004
Sequence was last modified on May 10, 2004 (Sequence version 2)
Annotations were last modified on    November 25, 2008 (Entry version 45)
Name and origin of the protein
Protein name Glyoxylate reductase
Synonym EC 1.1.1.26
Gene name
Name: gyaR
OrderedLocusNames: APE_1831.1
From
Aeropyrum pernix [TaxID: 56636] [HAMAP proteome]
Taxonomy Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales; Desulfurococcaceae; Aeropyrum.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K1;
DOI=10.1093/dnares/6.2.83; PubMed=10382966 [NCBI, ExPASy, EBI, Israel, Japan]
Kawarabayasi Y., Hino Y., Horikawa H., Yamazaki S., Haikawa Y., Jin-no K., Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A., Fukui S., Nagai Y., Nishijima K., Nakazawa H., Takamiya M., Masuda S., Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Kubota K., Nakamura Y., Nomura N., Sako Y., Kikuchi H.;
"Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1.";
DNA Res. 6:83-101(1999).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000002; BAA80834.2; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR E72568; E72568.
RefSeq NP_148197.2; -.
3D structure databases
HSSP Q9Z2F5; 1HL3. [HSSP ENTRY / PDB]
ModBase Q9YAW4.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0047964; Molecular function: glyoxylate reductase activity (inferred from electronic annotation from HAMAP).
GO:0051287; Molecular function: NAD binding (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_00776; -; 1.
PBIL [Tree]
InterPro IPR006139; D-isomer_2_OHA_DHase.
IPR006140; D-isomer_2_OHA_DHase_NAD-bd.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF00389; 2-Hacid_dh; 1.
PF02826; 2-Hacid_dh_C; 1.
Pfam graphical view of domain structure.
PROSITE PS00065; D_2_HYDROXYACID_DH_1; 1.
PS00670; D_2_HYDROXYACID_DH_2; 1.
PS00671; D_2_HYDROXYACID_DH_3; 1.
ProtoNet Q9YAW4.
Genome annotation databases
GeneID 1446271; -.
GenomeReviews BA000002_GR; APE_1831.1.
KEGG ape:APE_1831.1; -.
NMPDR fig|272557.1.peg.1305; -.
Phylogenomic databases
HOGENOM Q9YAW4; -.
Genome annotation databases
CMR Q9YAW4; APE_1831.1.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   335  335     Glyoxylate reductase. PRO_0000075946
NP_BIND   159   162  4     NADP (By similarity). 
NP_BIND   181   183  3     NADP (By similarity). 
NP_BIND   240   242  3     NADP (By similarity). 
NP_BIND   290   292  3     NADP (By similarity). 
ACT_SITE   242   242        By similarity. 
ACT_SITE   271   271        By similarity. 
ACT_SITE   290   290        Proton donor (By similarity). 
Sequence information
Length: 335 AA [This is the length of the unprocessed precursor] Molecular weight: 37757 Da [This is the MW of the unprocessed precursor] CRC64: 0CD5EE38E1AA6163 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MKRPRVFVTR EVFPEALELL SKYYDVEVWD KYQPPPYETL LSKAREADAL YTLLTDRIDC 

        70         80         90        100        110        120 
DLLSQAPRLR IVAQMAVGFD NIDVECATRL GIYVTNTPGV LTEATAEFTW ALILAAARRV 

       130        140        150        160        170        180 
VEADHFVRWG EWWRLRTGWH PMMMLGVELR GKTLGILGMG RIGSRVAEIG KAFGMRIIYH 

       190        200        210        220        230        240 
SRSRKREIEK ELGAEYRSLE DLLRESDILS IHLPLTDETR HLIGESELKL MKKTAILVNT 

       250        260        270        280        290        300 
GRGAIVDTGA LVKALREGWI AAAALDVFEE EPLNPNHPLT AFKNVVLAPH AASATRETRL 

       310        320        330 
RMAMMAAENL VAFAQGKVPP NLVNREVVKV RQPGF
Q9YAW4 in FASTA format

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