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UniProtKB/Swiss-Prot entry Q9FY99


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G6PD2_ARATH
Primary accession number Q9FY99
Secondary accession numbers Q43728 Q8VZD6
Integrated into Swiss-Prot on November 25, 2002
Sequence was last modified on November 25, 2002 (Sequence version 2)
Annotations were last modified on    November 25, 2008 (Entry version 68)
Name and origin of the protein
Protein name Glucose-6-phosphate 1-dehydrogenase 2, chloroplastic [Precursor]
Synonyms G6PDH2
G6PD2
EC 1.1.1.49
Gene name
OrderedLocusNames: At5g13110
ORFNames: T19L5_70
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/35048507; PubMed=11130714 [NCBI, ExPASy, EBI, Israel, Japan]
Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K., Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.;
"Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
Nature 408:823-826(2000).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
[3]
NUCLEOTIDE SEQUENCE [MRNA] OF 105-596.
STRAIN=cv. Columbia;
Fink A., Greppin H., Tacchini P.;
"Nucleotide sequence of a cDNA encoding the glucose-6-phosphate dehydrogenase from Arabidopsis thaliana.";
Submitted (JAN-1995) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL391711; CAC05439.1; ALT_SEQ; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY065042; AAL57678.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
X84229; CAA59011.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S71245; S71245.
RefSeq NP_196815.2; -.
UniGene At.61
3D structure databases
HSSP P11413; 1QKI. [HSSP ENTRY / PDB]
ModBase Q9FY99.
Organism-specific databases
TAIR At5g13110; -.
Gene expression databases
ArrayExpress Q9FY99; -.
GermOnline AT5G13110; Arabidopsis thaliana.
Ontologies
GO
GO:0009507; Cellular component: chloroplast (inferred from electronic annotation from UniProtKB-KW).
GO:0005488; Molecular function: binding (inferred from electronic annotation from InterPro).
GO:0004345; Molecular function: glucose-6-phosphate dehydrogenase activity (inferred from electronic annotation from InterPro).
GO:0006006; Biological process: glucose metabolic process (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001282; Glc-6-P_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR23429; G6PDH; 1.
Pfam PF02781; G6PD_C; 1.
PF00479; G6PD_N; 1.
Pfam graphical view of domain structure.
PRINTS PR00079; G6PDHDRGNASE.
ProDom PD001129; G6PD; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00871; zwf; 1.
PROSITE PS00069; G6P_DEHYDROGENASE; 1.
ProtoNet Q9FY99.
Genome annotation databases
GeneID 831150; -.
GenomeReviews BA000015_GR; AT5G13110.
KEGG ath:AT5G13110; -.
NMPDR fig|3702.1.peg.23426; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Carbohydrate metabolism; Chloroplast; Complete proteome; Glucose metabolism; NADP; Oxidoreductase; Plastid; Transit peptide.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
TRANSIT   1    50  50     Chloroplast (Potential). 
CHAIN   51   596  546     Glucose-6-phosphate 1-dehydrogenase 2, chloroplastic. PRO_0000010436
ACT_SITE   345   345        Proton acceptor (By similarity). 
BINDING   118   118        NADP (By similarity). 
BINDING   150   150        NADP (By similarity). 
BINDING   283   283        Substrate (By similarity). 
BINDING   287   287        Substrate (By similarity). 
DISULFID   168   176        Redox modulation (By similarity). 
CONFLICT   145   145        I -> V (in Ref. 3; CAA59011). 
CONFLICT   190   190        H -> I (in Ref. 3; CAA59011). 
CONFLICT   201   201        T -> I (in Ref. 3; CAA59011). 
CONFLICT   489   489        L -> F (in Ref. 3; CAA59011). 
CONFLICT   542   542        D -> G (in Ref. 2; AAL57678). 
Sequence information
Length: 596 AA [This is the length of the unprocessed precursor] Molecular weight: 67160 Da [This is the MW of the unprocessed precursor] CRC64: BDD89BEB49EF6E3B [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAALSSSVTT RSYHSGYLAS FSPVNGDRHR SLSFLSASPQ GLNPLDLCVR FQRKSGRASV 

        70         80         90        100        110        120 
FMQDGAIVTN SNSSESKTSL KGLKDEVLSA LSQEAAKVGV ESDGQSQSTV SITVVGASGD 

       130        140        150        160        170        180 
LAKKKIFPAL FALYYEGCLP EHFTIFGYSR SKMTDVELRN MVSKTLTCRI DKRANCGEKM 

       190        200        210        220        230        240 
EEFLKRCFYH SGQYDSQEHF TELDKKLKEH EAGRISNRLF YLSIPPNIFV DAVKCASTSA 

       250        260        270        280        290        300 
SSVNGWTRVI VEKPFGRDSE TSAALTKSLK QYLEEDQIFR IDHYLGKELV ENLSVLRFSN 

       310        320        330        340        350        360 
LIFEPLWSRQ YIRNVQFIFS EDFGTEGRGG YFDNYGIIRD IMQNHLLQIL ALFAMETPVS 

       370        380        390        400        410        420 
LDAEDIRNEK VKVLRSMRPI RVEDVVIGQY KSHTKGGVTY PAYTDDKTVP KGSLTPTFAA 

       430        440        450        460        470        480 
AALFIDNARW DGVPFLMKAG KALHTRSAEI RVQFRHVPGN LYNRNTGSDL DQATNELVIR 

       490        500        510        520        530        540 
VQPDEAIYLK INNKVPGLGM RLDRSNLNLL YSARYSKEIP DAYERLLLDA IEGERRLFIR 

       550        560        570        580        590 
SDELDAAWSL FTPLLKEIEE KKRIPEYYPY GSRGPVGAHY LAAKHKVQWG DVSIDQ 

Q9FY99 in FASTA format

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