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UniProtKB/Swiss-Prot entry Q9AC57

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AROE_CAUCR
Primary accession number Q9AC57
Secondary accession numbers None
Integrated into Swiss-Prot on October 19, 2002
Sequence was last modified on June 1, 2001 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 50)
Name and origin of the protein
Protein name Shikimate dehydrogenase
Synonym EC 1.1.1.25
Gene name
Name: aroE
OrderedLocusNames: CC_0003
From
Caulobacter crescentus (Caulobacter vibrioides) [TaxID: 155892] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales; Caulobacteraceae; Caulobacter.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 19089 / CB15;
DOI=10.1073/pnas.061029298; PubMed=11259647 [NCBI, ExPASy, EBI, Israel, Japan]
Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E., Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R., Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B., DeBoy R.T., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R., Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O., Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M.;
"Complete genome sequence of Caulobacter crescentus.";
Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE005673; AAK21991.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR C87249; C87249.
RefSeq NP_418823.1; -.
3D structure databases
HSSP P43876; 1P77. [HSSP ENTRY / PDB]
ModBase Q9AC57.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from InterPro).
GO:0050661; Molecular function: NADP binding (inferred from electronic annotation from InterPro).
GO:0004764; Molecular function: shikimate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0009073; Biological process: aromatic amino acid family biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_00222; -; 1.
PBIL [Tree]
InterPro IPR016040; NAD(P)-bd.
IPR011342; Quinate/shikimate_5-DHase.
IPR013708; Shikimate_DHase-bd_N.
IPR006151; Shikm_DHase/Glu-tRNA_Rdtase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF01488; Shikimate_DH; 1.
PF08501; Shikimate_dh_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00507; aroE; 1.
ProtoNet Q9AC57.
Genome annotation databases
GeneID 944079; -.
GenomeReviews AE005673_GR; CC_0003.
KEGG ccr:CC_0003; -.
NMPDR fig|190650.1.peg.3; -.
TIGR CC_0003; -.
Phylogenomic databases
HOGENOM Q9AC57; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   285  285     Shikimate dehydrogenase. PRO_0000135998
NP_BIND   136   140  5     NADP (By similarity). 
ACT_SITE   73    73        Proton acceptor (Potential). 
Sequence information
Length: 285 AA [This is the length of the unprocessed precursor] Molecular weight: 29015 Da [This is the MW of the unprocessed precursor] CRC64: 91174F9C770C14FE [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTNAITGAAI VGGVCGQPIK HSMSPVIHNA WIAAAGLDAA YVPFAPAADR FETFVDGLRG 

        70         80         90        100        110        120 
GAVRGLNVTI PFKERALAVA DTASDLARMA GAANLLVFNE DGSVHADNTD GPGLLGAIAI 

       130        140        150        160        170        180 
QAPGFDVTAA PVVILGAGGA ARGAVAALLL AGAPRIAVVN RTVARAQDLA DTFGEKVVAK 

       190        200        210        220        230        240 
GEDALPALLP EAGLIINATS LGLGGGAGPS ADLTLTPKTA VVMDMVYKPL RTEFLRRAEA 

       250        260        270        280 
AGRRTVDGLE MLLRQAIPTF ETIYGQAPSP KIDVRVLALK LLGEV
Q9AC57 in FASTA format

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