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UniProtKB/Swiss-Prot entry Q97YJ9


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ILVC2_SULSO
Primary accession number Q97YJ9
Secondary accession numbers None
Integrated into Swiss-Prot on August 29, 2001
Sequence was last modified on August 29, 2001 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 47)
Name and origin of the protein
Protein name Putative ketol-acid reductoisomerase 2
Synonyms EC 1.1.1.86
Acetohydroxy-acid isomeroreductase 2
Alpha-keto-beta-hydroxylacil reductoisomerase 2
Gene name
Name: ilvC2
Synonyms: ilvC-2
OrderedLocusNames: SSO1322
From
Sulfolobus solfataricus [TaxID: 2287] [HAMAP proteome]
Taxonomy Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 35092 / DSM 1617 / JCM 11322 / P2;
DOI=10.1073/pnas.141222098; PubMed=11427726 [NCBI, ExPASy, EBI, Israel, Japan]
She Q., Singh R.K., Confalonieri F., Zivanovic Y., Allard G., Awayez M.J., Chan-Weiher C.C.-Y., Clausen I.G., Curtis B.A., De Moors A., Erauso G., Fletcher C., Gordon P.M.K., Heikamp-de Jong I., Jeffries A.C., Kozera C.J., Medina N., Peng X., Thi-Ngoc H.P., Redder P., Schenk M.E., Theriault C., Tolstrup N., Charlebois R.L., Doolittle W.F., Duguet M., Gaasterland T., Garrett R.A., Ragan M.A., Sensen C.W., Van der Oost J.;
"The complete genome of the crenarchaeon Sulfolobus solfataricus P2.";
Proc. Natl. Acad. Sci. U.S.A. 98:7835-7840(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE006746; AAK41560.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A99288; A99288.
RefSeq NP_342770.1; -.
3D structure databases
HSSP Q9HVA2; 1NP3. [HSSP ENTRY / PDB]
ModBase Q97YJ9.
Enzyme and pathway databases
BioCyc SSOL273057:SSO1322-MON; -.
Ontologies
GO
GO:0005488; Molecular function: binding (inferred from electronic annotation from InterPro).
GO:0004455; Molecular function: ketol-acid reductoisomerase activity (inferred from electronic annotation from HAMAP).
GO:0009097; Biological process: isoleucine biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0009099; Biological process: valine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00435; atypical; 1.
PBIL [Tree]
InterPro IPR013023; AcH_isomrdctse.
IPR000506; AcH_isomrdctse_C.
IPR013116; IlvN.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR21371; AcH_isomrdctse; 1.
Pfam PF01450; IlvC; 1.
PF07991; IlvN; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00465; ilvC; 1.
ProtoNet Q97YJ9.
Genome annotation databases
GeneID 1454339; -.
GenomeReviews AE006641_GR; SSO1322.
KEGG sso:SSO1322; -.
NMPDR fig|273057.1.peg.1193; -.
Phylogenomic databases
HOGENOM Q97YJ9; -.
Genome annotation databases
CMR Q97YJ9; SSO1322.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   333  333     Putative ketol-acid reductoisomerase 2. PRO_0000151401
Sequence information
Length: 333 AA [This is the length of the unprocessed precursor] Molecular weight: 37185 Da [This is the MW of the unprocessed precursor] CRC64: D37083F704B95CA0 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MDKTVLDANL DPLKGKTIGV IGYGNQGRVQ ATIMRENGLN VIVGNVKDKY YELAKKEGFE 

        70         80         90        100        110        120 
VYEIDEAVRR SDVALLLIPD EVMKEVYEKK IAPVLQGKKE FVLDFASGYN VAFGLIRPPK 

       130        140        150        160        170        180 
SVDTIMVAPR MVGEGIMDLH KQGKGYPVLL GVKQDASGKA WDYAKAIAKG IGAIPGGIAV 

       190        200        210        220        230        240 
ISSFEEEALL DLMSEHTWVP ILFGAIKACY DIAVKEYGVS PEAALLEFYA SGELAEIARL 

       250        260        270        280        290        300 
IAEEGIFNQM VHHSTTSQYG TLTRMFKYYD VVRRIVENEA KYIWDGSFAK EWSLEQQAGY 

       310        320        330 
PVFYRLWELA TQSEMAKAEK ELYKLLGRKV KND 

Q97YJ9 in FASTA format

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