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UniProtKB/Swiss-Prot entry Q0A4S2


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AROE_ALHEH
Primary accession number Q0A4S2
Secondary accession numbers None
Integrated into Swiss-Prot on March 18, 2008
Sequence was last modified on October 17, 2006 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 25)
Name and origin of the protein
Protein name Shikimate dehydrogenase
Synonym EC 1.1.1.25
Gene name
Name: aroE
OrderedLocusNames: Mlg_2825
From
Alkalilimnicola ehrlichei (strain MLHE-1) [TaxID: 187272] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Chromatiales; Ectothiorhodospiraceae; Alkalilimnicola.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Oremland R.S., Hoeft S.E., Switzer-Blum J., Kulp T., King G., Tabita R., Witte B., Santini J.M., Basu P., Hollibaugh J.T., Xie G., Stolz J.F., Richardson P.;
"Complete sequence of Alkalilimnicola ehrilichei MLHE-1.";
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000453; ABI58165.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_743655.1; -.
3D structure databases
ModBase Q0A4S2.
Ontologies
GO
GO:0004764; Molecular function: shikimate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0009073; Biological process: aromatic amino acid family biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_00222; -; 1.
PBIL [Tree]
InterPro IPR016040; NAD(P)-bd.
IPR011342; Quinate/shikimate_5-DHase.
IPR013708; Shikimate_DHase-bd_N.
IPR006151; Shikm_DHase/Glu-tRNA_Rdtase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF01488; Shikimate_DH; 1.
PF08501; Shikimate_dh_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00507; aroE; 1.
BLOCKS Q0A4S2.
ProtoNet Q0A4S2.
Genome annotation databases
GeneID 4270752; -.
GenomeReviews CP000453_GR; Mlg_2825.
KEGG aeh:Mlg_2825; -.
NMPDR fig|187272.6.peg.2699; -.
Phylogenomic databases
HOGENOM Q0A4S2; -.
Genome annotation databases
CMR Q0A4S2; Mlg_2825.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   270  270     Shikimate dehydrogenase. PRO_0000325097
NP_BIND   127   131  5     NADP (By similarity). 
ACT_SITE   66    66        Proton acceptor (Potential). 
Sequence information
Length: 270 AA [This is the length of the unprocessed precursor] Molecular weight: 28651 Da [This is the MW of the unprocessed precursor] CRC64: 5274D15E7FF18412 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTDRYAVMGN PIEHSKSPEI HRMFAEQTGQ AIAYERMRVP LEGFEPAVRA FFASGGKGLN 

        70         80         90        100        110        120 
ITVPFKEQAW VLVDRRAPRA ERAGAVNTLL AEAGRLVGDN TDGTGLVRDL TVNHGAALQG 

       130        140        150        160        170        180 
RRVLVIGAGG AVRGVLPALL PEAPGEVVIA NRTVARAEAL VELFADQGRL SAVGFDRLQG 

       190        200        210        220        230        240 
PFDVVINGTS AGLAGELPPL PDDLLAPGAT CYDMVYGDQP TPFVRWARAH GAAMAVDGLG 

       250        260        270 
MLVEQAAESF LIWRGVRPES APVIAALRPE 

Q0A4S2 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
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