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UniProtKB/Swiss-Prot entry Q06494


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PLR1_YEAST
Primary accession number Q06494
Secondary accession numbers None
Integrated into Swiss-Prot on October 31, 2006
Sequence was last modified on November 1, 1996 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 50)
Name and origin of the protein
Protein name Putative pyridoxal reductase
Synonyms PL reductase
PL-red
EC 1.1.1.65
Gene name
OrderedLocusNames: YPR127W
From
Saccharomyces cerevisiae (Baker's yeast) [TaxID: 4932] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 204511 / S288c / AB972;
PubMed=9169875 [NCBI, ExPASy, EBI, Israel, Japan]
Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W., Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D., Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E., Churcher C.M., Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H., DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N., Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K., Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M., Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A., Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S., Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D., Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S., Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B., Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A., Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R., Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A., Vo D.H., Hani J.;
"The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.";
Nature 387:103-105(1997).
[2]
SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
DOI=10.1038/nature02026; PubMed=14562095 [NCBI, ExPASy, EBI, Israel, Japan]
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.;
"Global analysis of protein localization in budding yeast.";
Nature 425:686-691(2003).
[3]
LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
DOI=10.1038/nature02046; PubMed=14562106 [NCBI, ExPASy, EBI, Israel, Japan]
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.;
"Global analysis of protein expression in yeast.";
Nature 425:737-741(2003).
[4]
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-87 AND THR-98, AND MASS SPECTROMETRY.
DOI=10.1074/mcp.M700468-MCP200; PubMed=18407956 [NCBI, ExPASy, EBI, Israel, Japan]
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
"A multidimensional chromatography technology for in-depth phosphoproteome analysis.";
Mol. Cell. Proteomics 7:1389-1396(2008).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U40828; AAB68066.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S69018; S69018.
RefSeq NP_015452.1; -.
3D structure databases
ModBase Q06494.
Protein-protein interaction databases
IntAct Q06494; -.
Organism-specific databases
CYGD YPR127w; -.
SGD S000006331; YPR127W.
Yeast-GFP YPR127W.
Gene expression databases
GermOnline YPR127W; Saccharomyces cerevisiae.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from direct assay from SGD).
GO:0005634; Cellular component: nucleus (inferred from direct assay from SGD).
QuickGo view.
Family and domain databases
InterPro IPR001395; Aldo/ket_red.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.100; Aldo/ket_red; 1.
PANTHER PTHR11732; Aldo/ket_red; 1.
Pfam PF00248; Aldo_ket_red; 1.
Pfam graphical view of domain structure.
ProDom PD000288; Aldo/ket_red; 1.
[Domain structure / List of seq. sharing at least 1 domain]
PROSITE PS00798; ALDOKETO_REDUCTASE_1; FALSE_NEG.
PS00062; ALDOKETO_REDUCTASE_2; FALSE_NEG.
PS00063; ALDOKETO_REDUCTASE_3; FALSE_NEG.
BLOCKS Q06494.
ProtoNet Q06494.
Proteomic databases
PeptideAtlas Q06494; -.
Genome annotation databases
Ensembl YPR127W; Saccharomyces cerevisiae. [Contig view]
GeneID 856245; -.
GenomeReviews U00094_GR; YPR127W.
KEGG sce:YPR127W; -.
NMPDR fig|4932.3.peg.6589; -.
Phylogenomic databases
HOGENOM Q06494; -.
Other
LinkHub Q06494; -.
NextBio 981513; -.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; NADP; Nucleus; Oxidoreductase; Phosphoprotein.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
CHAIN   1   345  345     Putative pyridoxal reductase. PRO_0000257816
ACT_SITE   60    60        Proton donor (By similarity). 
MOD_RES   87    87        Phosphoserine. 
MOD_RES   98    98        Phosphothreonine. 
Sequence information
Length: 345 AA [This is the length of the unprocessed precursor] Molecular weight: 38601 Da [This is the MW of the unprocessed precursor] CRC64: C443ED79F25EA106 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSVADLKNNI HKLDTGYGLM SLTWRAEPIP QSQAFEAMHR VVELSRERGH KAFFNVGEFY 

        70         80         90        100        110        120 
GPDFINLSYV HDFFAKYPDL RKDVVISCKG GADNATLTPR GSHDDVVQSV KNSVSAIGGY 

       130        140        150        160        170        180 
IDIFEVARID TSLCTKGEVY PYESFEALAE MISEGVIGGI SLSEVNEEQI RAIHKDWGKF 

       190        200        210        220        230        240 
LTCVEVELSL FSNDILHNGI AKTCAELGLS IICYSPLGRG LLTGQLKSNA DIPEGDFRKS 

       250        260        270        280        290        300 
LKRFSDESLK KNLTLVRFLQ EEIVDKRPQN NSITLAQLAL GWVKHWNKVP EYSGAKFIPI 

       310        320        330        340 
PSGSSISKVN ENFDEQKTKL TDQEFNAINK YLTTFHTVGD RYEMA 

Q06494 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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