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UniProtKB/Swiss-Prot entry Q04795


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AK1_BACSU
Primary accession number Q04795
Secondary accession number O31759
Integrated into Swiss-Prot on October 1, 1993
Sequence was last modified on May 30, 2000 (Sequence version 2)
Annotations were last modified on    November 4, 2008 (Entry version 69)
Name and origin of the protein
Protein name Aspartokinase 1
Synonyms EC 2.7.2.4
Aspartokinase I
Aspartate kinase 1
Gene name
Name: dapG
Synonyms: lssD
OrderedLocusNames: BSU16760
From
Bacillus subtilis [TaxID: 1423] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=168;
PubMed=8098035 [NCBI, ExPASy, EBI, Israel, Japan]
Chen N.-Y., Jiang S.-Q., Klein D.A., Paulus H.;
"Organization and nucleotide sequence of the Bacillus subtilis diaminopimelate operon, a cluster of genes encoding the first three enzymes of diaminopimelate synthesis and dipicolinate synthase.";
J. Biol. Chem. 268:9448-9465(1993).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=168;
DOI=10.1038/36786; PubMed=9384377 [NCBI, ExPASy, EBI, Israel, Japan]
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.;
"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.";
Nature 390:249-256(1997).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
L08471; AAA22384.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z99112; CAB13549.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR C46665; C46665.
RefSeq NP_389558.1; -.
3D structure databases
ModBase Q04795.
Enzyme and pathway databases
BioCyc BSUB224308:BSU1677-MON; -.
Organism-specific databases
SubtiList BG10784; dapG. [Micado]
Ontologies
GO
GO:0019877; Biological process: diaminopimelate biosynthetic process (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001048; Asp/Glu/Uridylate_kinase.
IPR005260; Asp_kin_monofn.
IPR001341; Asp_kin_reg.
IPR001057; Glu_5kinase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.1160.10; Aa_kinase; 1.
Pfam PF00696; AA_kinase; 1.
Pfam graphical view of domain structure.
PRINTS PR00474; GLU5KINASE.
TIGRFAMs TIGR00656; asp_kin_monofn; 1.
TIGR00657; asp_kinases; 1.
PROSITE PS00324; ASPARTOKINASE; 1.
BLOCKS Q04795.
ProtoNet Q04795.
Genome annotation databases
GeneID 936710; -.
GenomeReviews AL009126_GR; BSU16760.
KEGG bsu:BSU16760; -.
NMPDR fig|224308.1.peg.1679; -.
Phylogenomic databases
HOGENOM Q04795; -.
Genome annotation databases
CMR Q04795; BSU16760.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Alternative initiation; Amino-acid biosynthesis; Complete proteome; Diaminopimelate biosynthesis; Kinase; Lysine biosynthesis; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   404  404     Aspartokinase 1. PRO_0000002367
VAR_SEQ   1   244        Missing (in isoform Beta). VSP_018652
VAR_SEQ   245   245        V -> M (in isoform Beta). VSP_018985
CONFLICT   399   399        E -> V (in Ref. 1; AAA22384). 
Sequence information
Length: 404 AA [This is the length of the unprocessed precursor] Molecular weight: 42978 Da [This is the MW of the unprocessed precursor] CRC64: 49A6DA70D70047C4 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKIIVQKFGG TSVKDDKGRK LALGHIKEAI SEGYKVVVVV SAMGRKGDPY ATDSLLGLLY 

        70         80         90        100        110        120 
GDQSAISPRE QDLLLSCGET ISSVVFTSML LDNGVKAAAL TGAQAGFLTN DQHTNAKIIE 

       130        140        150        160        170        180 
MKPERLFSVL ANHDAVVVAG FQGATEKGDT TTIGRGGSDT SAAALGAAVD AEYIDIFTDV 

       190        200        210        220        230        240 
EGVMTADPRV VENAKPLPVV TYTEICNLAY QGAKVISPRA VEIAMQAKVP IRVRSTYSND 

       250        260        270        280        290        300 
KGTLVTSHHS SKVGSDVFER LITGIAHVKD VTQFKVPAKI GQYNVQTEVF KAMANAGISV 

       310        320        330        340        350        360 
DFFNITPSEI VYTVAGNKTE TAQRILMDMG YDPMVTRNCA KVSAVGAGIM GVPGVTSKIV 

       370        380        390        400 
SALSEKEIPI LQSADSHTTI WVLVHEADMV PAVNALHEEF ELSK 

Q04795 in FASTA format

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