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UniProtKB/Swiss-Prot entry P97324

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G6PD2_MOUSE
Primary accession number P97324
Secondary accession numbers None
Integrated into Swiss-Prot on December 15, 1998
Sequence was last modified on January 23, 2007 (Sequence version 3)
Annotations were last modified on    November 4, 2008 (Entry version 75)
Name and origin of the protein
Protein name Glucose-6-phosphate 1-dehydrogenase 2
Synonyms G6PD
EC 1.1.1.49
Gene name
Name: G6pd2
Synonyms: G6pd-2
From
Mus musculus (Mouse) [TaxID: 10090] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=Swiss;
DOI=10.1006/geno.1997.4673; PubMed=9169132 [NCBI, ExPASy, EBI, Israel, Japan]
Hendriksen P.J.M., Hoogerbrugge J.W., Baarends W.M., de Boer P., Vreeburg J.T.M., Vos E.A., van der Lende T., Grootegoed A.J.;
"Testis-specific expression of a functional retroposon encoding glucose-6-phosphate dehydrogenase in the mouse.";
Genomics 41:350-359(1997).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
Z84471; CAB06476.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_062341.1; -.
UniGene Mm.347430
3D structure databases
HSSP P11413; 1QKI. [HSSP ENTRY / PDB]
SMR P97324; 28-513.
ModBase P97324.
PTM databases
PhosphoSite P97324; -.
Organism-specific databases
MGI MGI:105977; G6pd2.
Gene expression databases
ArrayExpress P97324; -.
CleanEx MM_G6PD2; -.
GermOnline ENSMUSG00000045120; Mus musculus.
Ontologies
GO
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001282; Glc-6-P_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR23429; G6PDH; 1.
Pfam PF02781; G6PD_C; 1.
PF00479; G6PD_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000110; G6PD; 1.
PRINTS PR00079; G6PDHDRGNASE.
ProDom PD001129; G6PD; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00871; zwf; 1.
BLOCKS P97324.
ProtoNet P97324.
Genome annotation databases
Ensembl ENSMUSG00000031400; Mus musculus. [Contig view]
GeneID 14380; -.
KEGG mmu:14380; -.
Phylogenomic databases
HOGENOM P97324; -.
HOVERGEN P97324; -.
Other
NextBio 285889; -.
SOURCE G6pd2; Mus musculus.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Acetylation; Carbohydrate metabolism; Glucose metabolism; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
INIT_MET   1     1        Removed (By similarity). 
CHAIN   2   513  512     Glucose-6-phosphate 1-dehydrogenase 2. PRO_0000068086
ACT_SITE   263   263        Proton acceptor (By similarity). 
BINDING   40    40        NADP (By similarity). 
BINDING   72    72        NADP (By similarity). 
BINDING   201   201        Substrate (By similarity). 
BINDING   205   205        Substrate (By similarity). 
BINDING   238   238        NADP (By similarity). 
BINDING   357   357        NADP (By similarity). 
BINDING   487   487        NADP (By similarity). 
MOD_RES   2     2        N-acetylalanine (By similarity). 
Sequence information
Length: 513 AA [This is the length of the unprocessed precursor] Molecular weight: 59126 Da [This is the MW of the unprocessed precursor] CRC64: 655830EB767B6C53 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAEQVTLSRT QVCGILREEL YQNDAFHQAD THIFIIMGAS GDLAKKKIYP TIWWLFRDGL 

        70         80         90        100        110        120 
LPKETFIVGY ARSQLTVDDI QKQSEPFFKA TPEERPKLEE FFTRNSYVVG QYDDPASYKH 

       130        140        150        160        170        180 
LNSYINALHQ GMQANHLFYL ALPPTVYEAV TKNIQETCMS QTGFNRIIVE KPFGRDLQSS 

       190        200        210        220        230        240 
NQLSNHISSL FREDQIYRID HYLDKEMVQN LMVLRFANRI FGPIWNGDNI VCVILTFKEP 

       250        260        270        280        290        300 
FGTEGRGGYF DEFGIIRDVM QSHLLQMLCL VAMEKPATTD SDDVRNEKVK VLKCISEVET 

       310        320        330        340        350        360 
DNVILGQYVG NPNGEGEAAN GYLDDPTVPR GSTTATFAAA VLYVKNERWD GVPFILRCGK 

       370        380        390        400        410        420 
ALNERKAEVR LQFRDIPGDI FHQKCKRNEL VIRMQPNEAV YTTMMTKKPG MFFNPEESEL 

       430        440        450        460        470        480 
DLTYGNKYKN VKLPGAYERL ILDVFCGCQM HFVRTDELRE GWRIFTPLLH KIEREKPQPF 

       490        500        510 
PYVYGSRGPT EADELMRRVG FQYKGTYKGT HKH
P97324 in FASTA format

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