PROTEIN SEQUENCE, SUBCELLULAR LOCATION, AND ANTIGENICITY.
STRAIN=SC5314;
TISSUE=Protoplast;
DOI=10.1002/pmic.200400903; PubMed=15378761 [NCBI, ExPASy, EBI, Israel, Japan]
Pitarch A., Abian J., Carrascal M., Sanchez M., Nombela C., Gil C.;
"Proteomics-based identification of novel Candida albicans antigens for diagnosis of systemic candidiasis in patients with underlying hematological malignancies.";
Proteomics 4:3084-3106(2004).

Comments

CATALYTIC ACTIVITY: (S)-malate + NAD⁺ = oxaloacetate + NADH.
SUBUNIT: Homodimer (By similarity).
SUBCELLULAR LOCATION: Cytoplasm.
MISCELLANEOUS: Has antigenic properties. Elicits a specific immune response in systemic candidiasis human patients undergoing malignant hematological disorders.
SIMILARITY: Belongs to the LDH/MDH superfamily. MDH type 1 family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

3D structure databases

ModBase

P83778.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-KW).
GO:0055114;	Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0006099;	Biological process: tricarboxylic acid cycle (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

InterPro

IPR001252; Malate_DHase_AS.
IPR010097; Malate_DHase_NAD-dep_euk_g_bac.
Graphical view of domain structure.

PANTHER

PTHR11540:SF1; MDH_euk_g_bac; 1.

PROSITE

PS00068; MDH; PARTIAL.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Cytoplasm; Direct protein sequencing; NAD; Oxidoreductase; Tricarboxylic acid cycle.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`<1 >51`	`>51`	`Malate dehydrogenase, cytoplasmic.`	`PRO_0000113337`
`NON_CONS`	`10 11`
`NON_CONS`	`27 28`
`NON_CONS`	`37 38`
`NON_TER`	`1 1`
`NON_TER`	`51 51`

Sequence information

Length: 51 AA [This is the length of the partial sequence of the unprocessed precursor]

Molecular weight: 5229 Da [This is the MW of the partial sequence of the unprocessed precursor]

CRC64: 0617C24C3C61ACAD [This is a checksum on the sequence]

        10         20         30         40         50 
VTDLALYDIR PGVAADVSHV PTNSTVKLFN TNASIVRAGS ATLSMAQAGA R

P83778 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools