ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry P83373

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name MDHM_FRAAN
Primary accession number P83373
Secondary accession numbers None
Integrated into Swiss-Prot on November 1, 2002
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 47)
Name and origin of the protein
Protein name Malate dehydrogenase, mitochondrial [Precursor]
Synonym EC 1.1.1.37
Gene name
Name: MMDHI
From
Fragaria ananassa (Strawberry) [TaxID: 3747] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids I; Rosales; Rosaceae; Rosoideae; Fragaria.
Protein existence 1: Evidence at protein level;
References
[1]
 NUCLEOTIDE SEQUENCE, AND PROTEIN SEQUENCE OF 20-37.
STRAIN=cv. Elsanta;
TISSUE=Fruit;
DOI=10.1111/j.0031-9317.2004.00302.x; PubMed=15086813 [NCBI, ExPASy, EBI, Israel, Japan]
Iannetta P.P.M., Escobar N.M., Ross H.A., Souleyre E.J., Hancock R.D., Witte C.P., Davies H.V.;
"Identification, cloning and expression analysis of strawberry (Fragaria x ananassa) mitochondrial citrate synthase and mitochondrial malate dehydrogenase.";
Physiol. Plantarum 121:15-26(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
3D structure databases
HSSP P00346; 1MLD. [HSSP ENTRY / PDB]
ModBase P83373.
Ontologies
GO
GO:0005759; Cellular component: mitochondrial matrix (inferred from electronic annotation from UniProtKB-SubCell).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0006099; Biological process: tricarboxylic acid cycle (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001557; L-lactate/malate_DHase.
IPR001236; Lactate/malate_DHase.
IPR015955; Lactate_DHase/Glyco_Ohase_4_C.
IPR001252; Malate_DHase_AS.
IPR010097; Malate_DHase_NAD-dep_euk_g_bac.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.90.110.10; lact_mal_DH; 1.
G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR11540:SF1; MDH_euk_g_bac; 1.
Pfam PF02866; Ldh_1_C; 1.
PF00056; Ldh_1_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000102; Lac_mal_DH; 1.
TIGRFAMs TIGR01772; MDH_euk_gproteo; 1.
PROSITE PS00068; MDH; 1.
BLOCKS P83373.
ProtoNet P83373.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Direct protein sequencing; Mitochondrion; NAD; Oxidoreductase; Transit peptide; Tricarboxylic acid cycle.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
TRANSIT   1    19  19     Mitochondrion. 
CHAIN   20   339  320     Malate dehydrogenase, mitochondrial. PRO_0000018627
NP_BIND   33    39  7     NAD (By similarity). 
NP_BIND   142   144  3     NAD (By similarity). 
ACT_SITE   202   202        Proton acceptor (By similarity). 
BINDING   59    59        NAD (By similarity). 
BINDING   106   106        Substrate (By similarity). 
BINDING   112   112        Substrate (By similarity). 
BINDING   119   119        NAD (By similarity). 
BINDING   144   144        Substrate (By similarity). 
BINDING   178   178        Substrate (By similarity). 
BINDING   253   253        NAD (By similarity). 
Sequence information
Length: 339 AA [This is the length of the unprocessed precursor] Molecular weight: 35622 Da [This is the MW of the unprocessed precursor] CRC64: 22D4EF65E225A00C [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MRPSMSLIRS VSRVARRGYS SESVPQRKVA VLGAAGGIGQ PLALLMKLNP LVSQLSLYDI 

        70         80         90        100        110        120 
AGTPGVAADV SHINTRSEVK GYAGEEQLGE ALEGCDVVII PAGVPRKPGM TRDDLFNINA 

       130        140        150        160        170        180 
GIVRSLTAAI AKYCPHAIIN MISNPVNSTV PIASEVLKKA GVYDEKKLFG VTTLDVVRAK 

       190        200        210        220        230        240 
TFYAGKAGVP VAEVNVPVVG GHAGITILPL FSQATPKANL SDDYIKALTK RTQDGGTEVV 

       250        260        270        280        290        300 
EAKAGKGSAT LSMAYAGALF ADACLXGLNG VPDVVECSYV QSSITELPFF ASKVRLGKNG 

       310        320        330 
VEEVLDLGPL SDFEKEGLKQ LKPELKSSIE KGIKFANQS
P83373 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by ch flag SIB Switzerland Mirror sites: Australia Brazil Canada China Korea
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!