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UniProtKB/Swiss-Prot entry P77809

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G6PD_ACTAC
Primary accession number P77809
Secondary accession numbers None
Integrated into Swiss-Prot on November 1, 1997
Sequence was last modified on February 1, 1997 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 49)
Name and origin of the protein
Protein name Glucose-6-phosphate 1-dehydrogenase
Synonyms G6PD
EC 1.1.1.49
Gene name
Name: zwf
From
Actinobacillus actinomycetemcomitans (Haemophilus actinomycetemcomitans) [TaxID: 714] 
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Aggregatibacter.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 43718 / FDC Y4 / Serotype b;
DOI=10.1006/bbrc.1996.5917; PubMed=9020051 [NCBI, ExPASy, EBI, Israel, Japan]
Yoshida Y., Nakano Y., Yamashita Y., Koga T.;
"The gnd gene encoding a novel 6-phosphogluconate dehydrogenase and its adjacent region of Actinobacillus actinomycetemcomitans chromosomal DNA.";
Biochem. Biophys. Res. Commun. 230:220-225(1997).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
D88189; BAA13554.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
HSSP P11413; 1QKI. [HSSP ENTRY / PDB]
ModBase P77809.
Ontologies
GO
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001282; Glc-6-P_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR23429; G6PDH; 1.
Pfam PF02781; G6PD_C; 1.
PF00479; G6PD_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000110; G6PD; 1.
PRINTS PR00079; G6PDHDRGNASE.
ProDom PD001129; G6PD; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00871; zwf; 1.
PROSITE PS00069; G6P_DEHYDROGENASE; 1.
BLOCKS P77809.
ProtoNet P77809.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Carbohydrate metabolism; Glucose metabolism; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   494  494     Glucose-6-phosphate 1-dehydrogenase. PRO_0000068108
ACT_SITE   242   242        Proton acceptor (By similarity). 
BINDING   14    14        NADP (By similarity). 
BINDING   46    46        NADP (By similarity). 
BINDING   180   180        Substrate (By similarity). 
BINDING   184   184        Substrate (By similarity). 
Sequence information
Length: 494 AA [This is the length of the unprocessed precursor] Molecular weight: 56385 Da [This is the MW of the unprocessed precursor] CRC64: B0B2A32F349936A2 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MKAENCCIVI FGASGDLTYR KLIPALYNLY KIDRLGEDFS VLGVARTELN DKSFREKMRQ 

        70         80         90        100        110        120 
TLIKNEGAKG ECLEQFCSHL YYQAVNTADK ADYAKLVPRL DELHDTYRTE GNTLYYLSTP 

       130        140        150        160        170        180 
PSLYGVIPEC LGEHGLNKED RGWKRLIVEK PFGYDRETAE ALDIQIHRFF EEHQIYRIDH 

       190        200        210        220        230        240 
YLGKETVQNL LVLRFSNGWF EPLWNRNFID YIEITGAESI GVEERGGYYD GSGAMRDMFQ 

       250        260        270        280        290        300 
NHLLQVLAMV AMEPPVIINA NSMRDEVAKV LHCLRPLTQE DVEHNLVLGQ YVAGEVDGEW 

       310        320        330        340        350        360 
VKGYLEEKGV PPYSTTETYM ALRCEIENWR WAGVPFYVRT GKRLPARVTE IVIHFKTTPH 

       370        380        390        400        410        420 
PVFSQNAPEN KLIIRIQPDE GISMRFGLKK PGAGFEAKEV SMDFRYADLA GATVMTAYER 

       430        440        450        460        470        480 
LLLDAMKGDA TLFARTDAVH AAWKFVQPIL NYKAQGGRLY DYEAGTWGPT AADKLIAKSG 

       490 
RVWRRPSGLM KKKV
P77809 in FASTA format

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