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UniProtKB/Swiss-Prot entry P73058

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HISX1_SYNY3
Primary accession number P73058
Secondary accession numbers None
Integrated into Swiss-Prot on July 15, 1998
Sequence was last modified on February 1, 1997 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 54)
Name and origin of the protein
Protein name Histidinol dehydrogenase 1
Synonyms HDH 1
EC 1.1.1.23
Gene name
Name: hisD1
Synonyms: hisD
OrderedLocusNames: slr1848
From
Synechocystis sp. (strain PCC 6803) [TaxID: 1148] [HAMAP proteome]
Taxonomy Bacteria; Cyanobacteria; Chroococcales; Synechocystis.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1093/dnares/3.3.109; PubMed=8905231 [NCBI, ExPASy, EBI, Israel, Japan]
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions.";
DNA Res. 3:109-136(1996).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000022; BAA17080.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S75166; S75166.
RefSeq NP_440400.1; -.
3D structure databases
HSSP P06988; 1K75. [HSSP ENTRY / PDB]
ModBase P73058.
Protein-protein interaction databases
IntAct P73058; -.
Enzyme and pathway databases
BioCyc SSP1148:SLR1848-MON; -.
Ontologies
GO
GO:0004399; Molecular function: histidinol dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0000105; Biological process: histidine biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_01024; atypical; 1.
PBIL [Tree]
InterPro IPR001692; Histidinol_DHase.
IPR012131; Hstdl_DHase_prok.
Graphical view of domain structure.
PANTHER PTHR21256:SF2; Hstdl_DH_prok; 1.
Pfam PF00815; Histidinol_dh; 1.
Pfam graphical view of domain structure.
PRINTS PR00083; HOLDHDRGNASE.
ProDom PD002680; Histidinol_dh; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00069; hisD; 1.
PROSITE PS00611; HISOL_DEHYDROGENASE; 1.
BLOCKS P73058.
ProtoNet P73058.
Genome annotation databases
GeneID 953700; -.
GenomeReviews BA000022_GR; slr1848.
KEGG syn:slr1848; -.
NMPDR fig|1148.1.peg.501; -.
Phylogenomic databases
HOGENOM P73058; -.
Genome annotation databases
CMR P73058; slr1848.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Histidine biosynthesis; Metal-binding; NAD; Oxidoreductase; Zinc.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   434  434     Histidinol dehydrogenase 1. PRO_0000135865
ACT_SITE   330   330        Proton acceptor (By similarity). 
ACT_SITE   331   331        Proton acceptor (By similarity). 
METAL   260   260        Zinc (By similarity). 
METAL   263   263        Zinc (By similarity). 
METAL   423   423        Zinc (By similarity). 
Sequence information
Length: 434 AA [This is the length of the unprocessed precursor] Molecular weight: 46534 Da [This is the MW of the unprocessed precursor] CRC64: 76F07AC33439B1E1 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTRILKLSHL TPQQLNQLKR RSEQNIDQAL AIAKEVIEQV KMEGDAGVLH YSRQFDFAGA 

        70         80         90        100        110        120 
TAENLRVSEA EFAEAEKLVD PELRRAVEHA FRNIEKVHAG QMPPPMHLAE IEPGVFAGEK 

       130        140        150        160        170        180 
ITPLPTVGLY VPRGKGAFPS MMLMLAVPAR VAGVKKIVVC TPPDKEGKVE PVSLVTARMA 

       190        200        210        220        230        240 
GVDEVYKLGG VQALAAIAYG TKTVSKVDKL IGPCSIYGAA AKRLLSGIVD VGLPAGPSES 

       250        260        270        280        290        300 
IVLADETTDP KLAALDLLIE AEHGSDSAAL LVTHSASLAE KALGYLGEYL EKLPPWRKKF 

       310        320        330        340        350        360 
CEDGLGSYGG ILLTDSLQAS LDFINDYAPE HLQVLTADPL KLVGKIDNAG EILLGNYTPS 

       370        380        390        400        410        420 
SAATYAIGVN AVLPTGGFAR SYSAVSVFDF LKRSTLAYLT EEGFAGVKET VTTLADYEDF 

       430 
PAHALAIRER ENLL
P73058 in FASTA format

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