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UniProtKB/Swiss-Prot entry P70718

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name 6PGD_ACTAC
Primary accession number P70718
Secondary accession numbers None
Integrated into Swiss-Prot on November 1, 1997
Sequence was last modified on February 1, 1997 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 48)
Name and origin of the protein
Protein name 6-phosphogluconate dehydrogenase, decarboxylating
Synonym EC 1.1.1.44
Gene name
Name: gnd
From
Actinobacillus actinomycetemcomitans (Haemophilus actinomycetemcomitans) [TaxID: 714] 
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Aggregatibacter.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 43718 / FDC Y4 / Serotype b;
DOI=10.1006/bbrc.1996.5917; PubMed=9020051 [NCBI, ExPASy, EBI, Israel, Japan]
Yoshida Y., Nakano Y., Yamashita Y., Koga T.;
"The gnd gene encoding a novel 6-phosphogluconate dehydrogenase and its adjacent region of Actinobacillus actinomycetemcomitans chromosomal DNA.";
Biochem. Biophys. Res. Commun. 230:220-225(1997).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
D88189; BAA13558.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR JC5282; JC5282.
3D structure databases
HSSP P00349; 2PGD. [HSSP ENTRY / PDB]
ModBase P70718.
Ontologies
GO
GO:0019521; Biological process: D-gluconate metabolic process (inferred from electronic annotation from UniProtKB-KW).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR006183; 6-phosphogluconate_DHase.
IPR006114; 6PGDH_C.
IPR006113; 6PGDH_decarbox.
IPR006115; 6PGDH_NAD-bd.
IPR006184; 6PGdom_BS.
IPR013328; DHase_multihelical.
IPR012284; Fibritin/6PGD_C-extension.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:1.20.5.320; Fibritin/6PGD_C-extension; 1.
G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:1.10.1040.10; Opine_DH; 1.
Pfam PF00393; 6PGD; 1.
PF03446; NAD_binding_2; 1.
Pfam graphical view of domain structure.
PRINTS PR00076; 6PGDHDRGNASE.
TIGRFAMs TIGR00873; gnd; 1.
PROSITE PS00461; 6PGD; 1.
BLOCKS P70718.
ProtoNet P70718.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Gluconate utilization; NADP; Oxidoreductase; Pentose shunt.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   484  484     6-phosphogluconate dehydrogenase, decarboxylating. PRO_0000090024
Sequence information
Length: 484 AA [This is the length of the unprocessed precursor] Molecular weight: 53289 Da [This is the MW of the unprocessed precursor] CRC64: F7BD0B2EA3BF624D [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSVKGDIGVI GLAVMGQNLI LNMNDHGFKV VAYNRTTSKV DEFLEGAAKG TNIIGAYSLE 

        70         80         90        100        110        120 
DLANKLEKPR KVMLMVRAGE VVDHFIDALL PHLEAGDIII DGGNSNYPDT NRRVAALREK 

       130        140        150        160        170        180 
GIRFIGTGVS GGEEGARHGP SIMPGGNEEA WQFVKPVLQA ISAKTEQGEP CCDWVGKDGA 

       190        200        210        220        230        240 
GHFVKMVHNG IEYGDMQLIC EAYQFLKEGV GLSDDELQAT FNEWRNTELD SYLIDITADI 

       250        260        270        280        290        300 
LGYKDADGSR LVDKVLDTAG QKGTGKWTGI NALDFGIPLT LITESVFARC VSAFKDQRVA 

       310        320        330        340        350        360 
ASKLFHKTIG KVEGDKKVWI EAVRKALLAS KIISYAQGFM LIREASEHFN WNINYGNTAL 

       370        380        390        400        410        420 
LWREGCIIRS RFLGNIRDAY EANPDLIFLG SDSYFKGILE NAMSDWRKVV AKSIEVGIPM 

       430        440        450        460        470        480 
PCMASAITFL DGYTSARLPA NLLQAQRDYF GAHTYERTDK PRGEFFHTNW TGRGGNTAST 


TYDV
P70718 in FASTA format

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