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UniProtKB/Swiss-Prot entry P59414

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AROE_BUCBP
Primary accession number P59414
Secondary accession numbers None
Integrated into Swiss-Prot on March 28, 2003
Sequence was last modified on March 28, 2003 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 42)
Name and origin of the protein
Protein name Shikimate dehydrogenase
Synonym EC 1.1.1.25
Gene name
Name: aroE
OrderedLocusNames: bbp_437
From
Buchnera aphidicola subsp. Baizongia pistaciae [TaxID: 135842] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Buchnera.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0235981100; PubMed=12522265 [NCBI, ExPASy, EBI, Israel, Japan]
van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F., Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J., Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A.;
"Reductive genome evolution in Buchnera aphidicola.";
Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE016826; AAO27143.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_778038.1; -.
3D structure databases
HSSP P15770; 1NYT. [HSSP ENTRY / PDB]
ModBase P59414.
Enzyme and pathway databases
BioCyc BAPH224915:BBP_437-MON; -.
Ontologies
GO
GO:0004764; Molecular function: shikimate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0009073; Biological process: aromatic amino acid family biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_00222; -; 1.
PBIL [Tree]
InterPro IPR016040; NAD(P)-bd.
IPR011342; Quinate/shikimate_5-DHase.
IPR013708; Shikimate_DHase-bd_N.
IPR006151; Shikm_DHase/Glu-tRNA_Rdtase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF01488; Shikimate_DH; 1.
PF08501; Shikimate_dh_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00507; aroE; 1.
BLOCKS P59414.
ProtoNet P59414.
Genome annotation databases
GeneID 1058638; -.
GenomeReviews AE016826_GR; bbp_437.
KEGG bab:bbp437; -.
Phylogenomic databases
HOGENOM P59414; -.
Genome annotation databases
CMR P59414; bbp_437.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   282  282     Shikimate dehydrogenase. PRO_0000135997
NP_BIND   132   136  5     NADP (By similarity). 
ACT_SITE   70    70        Proton acceptor (Potential). 
Sequence information
Length: 282 AA [This is the length of the unprocessed precursor] Molecular weight: 31975 Da [This is the MW of the unprocessed precursor] CRC64: 344F5BDC826A9327 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MVKHCIDQFC VFGNPINHTQ SPYIHSLFSK QTGIVYEYSA RLVPFKEFNS YVLNFFLNKG 

        70         80         90        100        110        120 
KGANITVPFK ENAYVISNNL TIRAKMSRAV NTFKKLHNNK ILGDNTDGIG VLHDLKRIKF 

       130        140        150        160        170        180 
IKSKFNRVLL IGAGGAARGI IFSLLSYGCS IVVLNRTITR ALQLVEDFKN VGSISIFKEK 

       190        200        210        220        230        240 
FASNYSFNLI INATTINICQ NSNLSTIKSL IHKDVYCYDI NYSIKHKYTE FLLWCIKNGA 

       250        260        270        280 
ICVSNGIGML VSQAAHSFYL WYGILPETNS IICKLNRQFY ML
P59414 in FASTA format

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