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UniProtKB/Swiss-Prot entry P57502

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CYSI_BUCAI
Primary accession number P57502
Secondary accession numbers None
Integrated into Swiss-Prot on December 1, 2000
Sequence was last modified on December 1, 2000 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 49)
Name and origin of the protein
Protein name Sulfite reductase [NADPH] hemoprotein beta-component
Synonyms SIR-HP
SIRHP
EC 1.8.1.2
Gene name
Name: cysI
OrderedLocusNames: BU427
From
Buchnera aphidicola subsp. Acyrthosiphon pisum (Acyrthosiphon pisum symbiotic bacterium) [TaxID: 118099] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Buchnera.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Tokyo 1998;
DOI=10.1038/35024074; PubMed=10993077 [NCBI, ExPASy, EBI, Israel, Japan]
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.;
"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS.";
Nature 407:81-86(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000003; BAB13125.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_240239.1; -.
3D structure databases
HSSP P17846; 1AOP. [HSSP ENTRY / PDB]
ModBase P57502.
Enzyme and pathway databases
BioCyc BSP107806:BU427-MON; -.
Ontologies
GO
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0004783; Molecular function: sulfite reductase (NADPH) activity (inferred from electronic annotation from HAMAP).
GO:0019344; Biological process: cysteine biosynthetic process (inferred from electronic annotation from UniProtKB-KW).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0000103; Biological process: sulfate assimilation (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01540; -; 1.
PBIL [Tree]
InterPro IPR011786; CysI.
IPR006066; Nir_Si_BS.
IPR006067; Nir_Sir_4Fe4S.
IPR005117; NiRdtase/SiRdtase_haem-b_fer.
Graphical view of domain structure.
Pfam PF01077; NIR_SIR; 1.
PF03460; NIR_SIR_ferr; 2.
Pfam graphical view of domain structure.
PRINTS PR00397; SIROHAEM.
TIGRFAMs TIGR02041; CysI; 1.
PROSITE PS00365; NIR_SIR; 1.
BLOCKS P57502.
ProtoNet P57502.
Genome annotation databases
GeneID 1109775; -.
GenomeReviews BA000003_GR; BU427.
KEGG buc:BU427; -.
Phylogenomic databases
HOGENOM P57502; -.
Genome annotation databases
CMR P57502; BU427.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
4Fe-4S; Amino-acid biosynthesis; Complete proteome; Cysteine biosynthesis; Heme; Iron; Iron-sulfur; Metal-binding; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   569  569     Sulfite reductase [NADPH] hemoprotein beta-component. PRO_0000199893
METAL   433   433        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   439   439        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   478   478        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   482   482        Iron (siroheme axial ligand) (By similarity). 
METAL   482   482        Iron-sulfur (4Fe-4S) (By similarity). 
Sequence information
Length: 569 AA [This is the length of the unprocessed precursor] Molecular weight: 65742 Da [This is the MW of the unprocessed precursor] CRC64: 7CC09375A08B8DAB [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MNKKFKKIVT EKKLTDAERI KENSNYLRGT ITDDLKNEIT NGFTGDNFSL IRFHGMYQQD 

        70         80         90        100        110        120 
DRDLRIERNE QKLEPRYAMM LRCRLPGGVI KAKKWLKIDY FASKYTLYGT IRLTNRQTFQ 

       130        140        150        160        170        180 
FHGILKKNLK DVHKMLHSIG LDSLATANDV NRNVLCTSNP MESLIHQEAY EWARKISNFL 

       190        200        210        220        230        240 
LPHTKAYAEI WLDQKKIVTT EKEPILGKTY LPRKFKTTVV IPPYNDVDLY ANDMNFVAIT 

       250        260        270        280        290        300 
KNEKIIGFNI LIGGGLSFIH GNKNTWPFLA TEIGYISVEN TLSIAKAIVT TQRDWGNRTD 

       310        320        330        340        350        360 
RANAKTRYTI NNFGLNEFKK EIEKRANVNL KPVREYSFIS RGDRFGWIKD INNNWSLTLF 

       370        380        390        400        410        420 
IQNGRIYDDN DKLFKSGLLK IANIHDGNFR ITSNQNIIIS EVSEKNKNKI EKIALSSGLI 

       430        440        450        460        470        480 
NKSTNLRKNS MACVSFPTCP LAMAEAERML SFFITQLENI MLKYGVEDEV IILRVSGCPN 

       490        500        510        520        530        540 
GCGRSLLAEI GLIGKSIGRY NLYIGGNRIG NRIPKIYKEN ITEQEILIHL KYLIKTWSNE 

       550        560 
RKNKEDFGDF IVRKEFVKEV INPVYDFWS
P57502 in FASTA format

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