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UniProtKB/Swiss-Prot entry P14062


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name 6PGD_SALTY
Primary accession number P14062
Secondary accession numbers None
Integrated into Swiss-Prot on January 1, 1990
Sequence was last modified on January 1, 1990 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 73)
Name and origin of the protein
Protein name 6-phosphogluconate dehydrogenase, decarboxylating
Synonym EC 1.1.1.44
Gene name
Name: gnd
OrderedLocusNames: STM2081
From
Salmonella typhimurium [TaxID: 602] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Salmonella.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=LT2;
DOI=10.1007/BF00330960; PubMed=2671649 [NCBI, ExPASy, EBI, Israel, Japan]
Reeves P., Stevenson G.;
"Cloning and nucleotide sequence of the Salmonella typhimurium LT2 gnd gene and its homology with the corresponding sequence of Escherichia coli K12.";
Mol. Gen. Genet. 217:182-184(1989).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=LT2;
PubMed=1938920 [NCBI, ExPASy, EBI, Israel, Japan]
Dykhuizen D.E., Green L.;
"Recombination in Escherichia coli and the definition of biological species.";
J. Bacteriol. 173:7257-7268(1991).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=LT2 / SGSC1412 / ATCC 700720;
DOI=10.1038/35101614; PubMed=11677609 [NCBI, ExPASy, EBI, Israel, Japan]
McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P., Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D., Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E., Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R., Wilson R.K.;
"Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
Nature 413:852-856(2001).
[4]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-57.
STRAIN=LT2;
DOI=10.1111/j.1365-2958.1991.tb00741.x; PubMed=1710759 [NCBI, ExPASy, EBI, Israel, Japan]
Jiang X.-M., Neal B., Santiago F., Lee S.J., Romana L.K., Reeves P.R.;
"Structure and sequence of the rfb (O antigen) gene cluster of Salmonella serovar typhimurium (strain LT2).";
Mol. Microbiol. 5:695-713(1991).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X15651; CAA33677.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
M64332; AAA27137.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE008792; AAL20985.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
X56793; CAA40131.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S04397; S04397.
RefSeq NP_461026.1; -.
3D structure databases
HSSP P00349; 2PGD. [HSSP ENTRY / PDB]
ModBase P14062.
Enzyme and pathway databases
BioCyc STYP99287:STM2081-MON; -.
Organism-specific databases
StyGene SG10146; gnd.
Ontologies
GO
GO:0019521; Biological process: D-gluconate metabolic process (inferred from electronic annotation from UniProtKB-KW).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR006183; 6-phosphogluconate_DHase.
IPR006114; 6PGDH_C.
IPR006113; 6PGDH_decarbox.
IPR006115; 6PGDH_NAD-bd.
IPR006184; 6PGdom_BS.
IPR013328; DHase_multihelical.
IPR012284; Fibritin/6PGD_C-extension.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:1.20.5.320; Fibritin/6PGD_C-extension; 1.
G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:1.10.1040.10; Opine_DH; 1.
Pfam PF00393; 6PGD; 1.
PF03446; NAD_binding_2; 1.
Pfam graphical view of domain structure.
PRINTS PR00076; 6PGDHDRGNASE.
TIGRFAMs TIGR00873; gnd; 1.
PROSITE PS00461; 6PGD; 1.
BLOCKS P14062.
ProtoNet P14062.
Genome annotation databases
GeneID 1253602; -.
GenomeReviews AE006468_GR; STM2081.
KEGG stm:STM2081; -.
NMPDR fig|99287.1.peg.2006; -.
Phylogenomic databases
HOGENOM P14062; -.
Genome annotation databases
CMR P14062; STM2081.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Gluconate utilization; NADP; Oxidoreductase; Pentose shunt.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   468  468     6-phosphogluconate dehydrogenase, decarboxylating. PRO_0000090047
Sequence information
Length: 468 AA [This is the length of the unprocessed precursor] Molecular weight: 51395 Da [This is the MW of the unprocessed precursor] CRC64: D8EBB53A2DAADBF7 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSKQQIGVVG MAVMGRNLAL NIESRGYTVS VFNRSREKTE EVIAENPGKK LVPYYTVKEF 

        70         80         90        100        110        120 
VESLETPRRI LLMVKAGAGT DAAIDSLKPY LEKGDIIIDG GNTFFQDTIR RNRELSAEGF 

       130        140        150        160        170        180 
NFIGTGVSGG EEGALKGPSI MPGGQKDAYE LVAPILTKIA AVAEDGEPCV TYIGADGAGH 

       190        200        210        220        230        240 
YVKMVHNGIE YGDMQLIAEA YSLLKGGLNL SNEELANTFT EWNNGELSSY LIDITKDIFT 

       250        260        270        280        290        300 
KKDEDGNYLV DVILDEAANK GTGKWTSQSA LDLGEPLSLI TESVFARYIS SLKAQRVAAS 

       310        320        330        340        350        360 
KVLSGPKAQP AGDKAEFIEK VRRALYLGKI VSYAQGFSQL RAASDEYHWD LNYGEIAKIF 

       370        380        390        400        410        420 
RAGCIIRAQF LQKITDAYAE NADIANLLLA PYFKKIADEY QQALRDVVAY AVQNGIPVPT 

       430        440        450        460 
FSAAVAYYDS YRAAVLPANL IQAQRDYFGA HTYKRTDKEG IFHTEWLE 

P14062 in FASTA format

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View entry in raw text format (no links)
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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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