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UniProtKB/Swiss-Prot entry A6TTL2

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ILVC_ALKMQ
Primary accession number A6TTL2
Secondary accession numbers None
Integrated into Swiss-Prot on February 5, 2008
Sequence was last modified on August 21, 2007 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 10)
Name and origin of the protein
Protein name Ketol-acid reductoisomerase
Synonyms EC 1.1.1.86
Acetohydroxy-acid isomeroreductase
Alpha-keto-beta-hydroxylacil reductoisomerase
Gene name
Name: ilvC
OrderedLocusNames: Amet_3402
From
Alkaliphilus metalliredigens (strain QYMF) [TaxID: 293826] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Alkaliphilus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Ye Q., Zhou J., Fields M., Richardson P.;
"Complete sequence of Alkaliphilus metalliredigens QYMF.";
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000724; ABR49530.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001321189.1; -.
3D structure databases
ModBase A6TTL2.
Ontologies
GO
GO:0004455; Molecular function: ketol-acid reductoisomerase activity (inferred from electronic annotation from HAMAP).
GO:0009097; Biological process: isoleucine biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0009099; Biological process: valine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00435; -; 1.
PBIL [Tree]
InterPro IPR013023; AcH_isomrdctse.
IPR000506; AcH_isomrdctse_C.
IPR013328; DHase_multihelical.
IPR013116; IlvN.
Graphical view of domain structure.
Gene3D G3DSA:1.10.1040.10; Opine_DH; 1.
PANTHER PTHR21371; AcH_isomrdctse; 1.
Pfam PF01450; IlvC; 1.
PF07991; IlvN; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00465; ilvC; 1.
BLOCKS A6TTL2.
ProtoNet A6TTL2.
Genome annotation databases
GeneID 5313482; -.
GenomeReviews CP000724_GR; Amet_3402.
KEGG amt:Amet_3402; -.
CMR A6TTL2; Amet_3402.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   333  333     Ketol-acid reductoisomerase. PRO_1000060224
ACT_SITE   108   108        Potential. 
Sequence information
Length: 333 AA [This is the length of the unprocessed precursor] Molecular weight: 36603 Da [This is the MW of the unprocessed precursor] CRC64: 8895EEEBFA48696B [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAKLYYEKDC NLEVLKGKKV AIIGYGSQGH AHALNLKNSG VDVVVGLYEG SKSWERAEAE 

        70         80         90        100        110        120 
GLKVAVASDA AAEADVVVIL VNDEKQVQVY EESIKPNLTA GKYLMFAHGF NIHYGQIVPS 

       130        140        150        160        170        180 
EDVNVFMVAP KGPGHTVRSQ YQEGKGVPCL VSVYQDATGN TMDVALAYAA GIGGARAGVL 

       190        200        210        220        230        240 
KTTFKEETET DLFGEQAVLC GGVTELMKVG FEVLVEAGYE PESAYFECVH EMKLIIDMVV 

       250        260        270        280        290        300 
EGGLGNMRQS ISDTAEYGDY SVGKRIITDE TKKEMKKVLH EVQDGTFARN WILENKANRP 

       310        320        330 
AFTARRRMEQ SHQVEVVGKE LRDMMSWSKQ SKK
A6TTL2 in FASTA format

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