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UniProtKB/Swiss-Prot entry A0KEX8

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AROE_AERHH
Primary accession number A0KEX8
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on December 12, 2006 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 20)
Name and origin of the protein
Protein name Shikimate dehydrogenase
Synonym EC 1.1.1.25
Gene name
Name: aroE
OrderedLocusNames: AHA_0266
From
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240) [TaxID: 380703] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales; Aeromonadaceae; Aeromonas.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.00621-06; PubMed=16980456 [NCBI, ExPASy, EBI, Israel, Japan]
Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.H., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
"Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades.";
J. Bacteriol. 188:8272-8282(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000462; ABK36524.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_854794.1; -.
3D structure databases
ModBase A0KEX8.
Ontologies
GO
GO:0004764; Molecular function: shikimate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0009073; Biological process: aromatic amino acid family biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_00222; -; 1.
PBIL [Tree]
InterPro IPR011342; Quinate/shikimate_5-DHase.
IPR013708; Shikimate_DHase-bd_N.
IPR006151; Shikm_DHase/Glu-tRNA_Rdtase.
Graphical view of domain structure.
Pfam PF01488; Shikimate_DH; 1.
PF08501; Shikimate_dh_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00507; aroE; 1.
BLOCKS A0KEX8.
ProtoNet A0KEX8.
Genome annotation databases
GeneID 4490197; -.
GenomeReviews CP000462_GR; AHA_0266.
KEGG aha:AHA_0266; -.
TIGR AHA_0266; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   273  273     Shikimate dehydrogenase. PRO_1000021253
NP_BIND   126   130  5     NADP (By similarity). 
ACT_SITE   65    65        Proton acceptor (Potential). 
Sequence information
Length: 273 AA [This is the length of the unprocessed precursor] Molecular weight: 29192 Da [This is the MW of the unprocessed precursor] CRC64: 7D837CC96DD7FED7 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MDRYLVFGHP VRHSKSPFIH TLFARQTQQE LEYGLAEPAV EEFATSLRAF FAQGGKGCNV 

        70         80         90        100        110        120 
TVPFKEQAFA LVDRLSPRAR RAGAVNTIKL TDDGVLLGDN TDGAGLVADL KAHGVALAGS 

       130        140        150        160        170        180 
RILLLGAGGA ARGALAPLLA EQPEALVIAN RTHARAEQLA AEFRDLGAVS AQTYERLGGH 

       190        200        210        220        230        240 
FDLIINSTSA SLQGELPPLV PALIHADIAI YDMMYGATDT PFIAWAKGQG ARQTVDGLGM 

       250        260        270 
LVEQAAEAFT VWRGIRPGTK QVLRELKRNL GTL
A0KEX8 in FASTA format

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