What is Swiss-Shop ?

All Results will be returned to the client via E-mail.

You MUST complete the fields E-mail address and Title of your query.

You may choose between Sequence/Pattern or KeyWord based searches.

• SEQUENCE: Submit either a UniProtKB/Swiss-Prot entry name (ID) or accession number (AC) or paste a raw sequence into the appropriate window. If you enter a UniProtKB/Swiss-Prot ID or AC number or your own protein sequence, Swiss-Shop will perform, at each biweekly update of UniProtKB/Swiss-Prot, a BLAST alignment of your sequence against the sequences that have been added in UniProtKB/Swiss-Prot since the last biweekly update. You will receive an email message containing a list of new sequences thus found to be similar to your specified protein (with a probability P(N) below a user-specified threshold that the alignment is real and not random).

  OR

• PATTERN: Submit a protein pattern in PROSITE format. If you enter a PROSITE ID or AC or your own pattern in PROSITE format, Swiss-Shop will scan this pattern, at each weekly update of UniProtKB/Swiss-Prot, against the sequences that have been added in UniProtKB/Swiss-Prot since the last weekly update. You will receive the list of new UniProtKB/Swiss-Prot entries matching your pattern.

  OR

• KEYWORD: You may search entries using Authors (RA lines of UniProtKB/Swiss-Prot), Taxonomy (OS,OG and OC lines) or Keywords (DE,CC and KW lines), Cross-references to other databases (DR) and terms appearing on the feature (FT) lines of UniProtKB/Swiss-Prot.

  NOTE: Horizontally, multiple query words are considered as logical "OR", while vertically they are considered as logical "AND".

  Example:

Sequence-based searches

Use one of the alignment tools (e.g. BLAST) in the section 'similarity searches' of the ExPASy tools page for what is called 'sequence-based search' in Swiss-Shop.

Pattern-based searches

Use the ScanProsite or ProfileScan tools (also accessible from the ExPASy tools page, section 'Pattern and profile searches') for what is called 'pattern-based search' in Swiss-Shop.

Keyword-based searches

You can go to the UniProtKB top page and search the database using the 'direct access' methods there, or follow the link to the Sequence Retrieval System SRS.