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The UniProtKB/Swiss-Prot Human Proteome Initiative
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HPI Status report

UniProtKB/Swiss-Prot Release 56.2 of 23-Sep-2008: 398181 entries (Release statistics)

Total number of manually annotated mammalian entries in UniProtKB/Swiss-Prot: 63,578

Total number of manually annotated HUMAN entries in UniProtKB/Swiss-Prot: 20,327

Annotation categories counts [total / unique] max per entry average per entry number of entries coverage
Additional isoforms due to alternative splicing, initiation or promoter usage: 13,524 33 0.67 7,143 35%
Variants (disease mutations and polymorphisms): 46,198 1305 2.27 8,989 44%
Post-translational modifications (experimentally proven or potential): 59,237 303 2.91 11,204 55%
References to published articles: 102,928 / 44,900 176 5.06 20,094 98%
Comment blocks: 110,547 / 40,383 32 5.44 19,603 96%
Feature lines: 476,772 4049 23.46 20,327 100%
Cross-references:
EMBL protein_ids: 129,735 / 129,212 723 6.38 20,201 99%
InterPro: 50,005 / 6,420 23 2.46 16,775 82%
PDB (3D-structures): 27,766 / 26,182 464 1.37 3,406 16%
MIM catalog of human genes and genetic disorders: 15,276 / 14,389 15 0.75 12,142 59%
HGNC gene nomenclature: 19,086 / 18,957 14 0.94 18,930 93%

Total number of manually annotated MOUSE entries in UniProtKB/Swiss-Prot: 15,925

Annotation categories counts [total / unique] max per entry average per entry number of entries coverage
Additional isoforms due to alternative splicing, initiation or promoter usage: 7,207 20 0.45 4,271 26%
Variants (disease mutations and polymorphisms): 1,160 37 0.07 361 2%
Post-translational modifications (experimentally proven or potential): 49,261 216 3.09 9,484 59%
References to published articles: 46,641 / 17,333 49 2.93 15,683 98%
Comment blocks: 79,766 / 31,800 22 5.01 15,560 97%
Feature lines: 244,761 612 15.37 15,925 100%
Cross-references:
EMBL protein_ids: 67,787 / 67,735 111 4.26 15,787 99%
InterPro: 40,916 / 6,251 18 2.57 13,901 87%
PDB (3D-structures): 4,618 / 4,316 232 0.29 878 5%
Mouse Genome Informatics: 15,757 / 15,691 12 0.99 15,705 98%

Total number of manually annotated RAT entries in UniProtKB/Swiss-Prot: 7,172

Annotation categories counts [total / unique] max per entry average per entry number of entries coverage
Additional isoforms due to alternative splicing, initiation or promoter usage: 1,367 18 0.19 767 10%
Variants (disease mutations and polymorphisms): 238 12 0.03 113 1%
Post-translational modifications (experimentally proven or potential): 25,059 204 3.49 4,779 66%
References to published articles: 14,955 / 9,287 25 2.09 6,746 94%
Comment blocks: 36,784 / 17,550 24 5.13 7,035 98%
Feature lines: 105,278 314 14.68 7,172 100%
Cross-references:
EMBL protein_ids: 14,634 / 14,619 152 2.04 7,097 98%
InterPro: 19,534 / 4,587 19 2.72 6,460 90%
PDB (3D-structures): 2,624 / 2,505 116 0.37 393 5%
Rat Genome Database: 7,052 / 7,032 3 0.98 7,047 98%

For more detailed information about the taxonomic distribution of UniProtKB/Swiss-Prot entries, see the corresponding section in the Release statistics.

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